Clean Water. Clean Kill.

Smarter Glyphosate Stewardship Starts Here.

Hard water, hidden tank mix factors, and poor conditioning can make or break glyphosate application – and most farmers don’t even realise it.

This hub is your go-to resource to understand, manage and overcome the water quality issues that quietly rob glyphosate performance.

From water testing and conditioning to product choice, mixing order, and WRAG guidelines – this is where smarter stewardship begins.

Download our Glyphosate Stewardship Guide now or keep reading below.

Download Stewardship Guide
UP TO
30%
LOSS IN WEED CONTROL

Why Water Quality Matters

Glyphosate is a polar molecule that binds with divalent cations like calcium and magnesium – common in hard water. When this happens, glyphosate forms insoluble salts and loses efficacy in the plant.

This phenomenon – often called “lock-up” – reduces uptake, slows translocation, and compromises weed control. The result? Patchy kills, regrowth, and increased selection pressure for resistance.

You could be losing up to 30% of your glyphosate’s power without knowing it.

Even clean water becomes problematic if not stored properly
If you're not testing your tank, you're risking your tank-mix
The Issue

<5% of Farmers Know the Hardness of their Water

In a recent survey of 128 farmers, just 4% knew the hardness of their spray water.

Water hardness varies hugely by source: borehole, mains, and rainwater all differ – and even the same source can shift over time.

Stored water (in tanks or pipes) can pick up additional minerals and contamination.

The problem?

This variation means guesswork isn’t good enough. If you under-dose a water conditioner, glyphosate gets locked up. If you overdose, you waste product and money.

Is Water Stealing Your Glyphosate?

  • Up to 30% efficacy can be lost to hard water
  • ~70% of farms In England use water that’s moderately hard to very hard
  • Even at 150ppm calcium carbonate you could be losing valuable efficacy
  • You could be losing £200+/ha in re-sprays, product waste and yield loss
  • Weakened sprays = weed survival = resistance pressure

Never
add glyphosate before conditioning
- or you risk wasting the chemistry
The Solution

Stewardship & Performance Starts in the Tank

Clean Water. Clean Kill - starts by testing and treating water first

  • Know your spray water – test don’t guess.
  • Treat the tank – conditioner hard water with a true water conditioner before glyphosate enters the tank
  • Protect your glyphosate – apply at the right time with the right time to get clean kill consistently.
Tip:
Hardness can vary by water source, storage tank, or time of year - re‑test regularly

Test Water Regularly

The key is to test your spray water before every campaign.

A simple digital meter measuring total dissolved solids (TDS) in ppm, gives a fast and accurate picture of water hardness. TDS is primarily dissolved minerals of calcium (Ca2+), magnesium (Mg2+) and iron (Fe3+) which make water hard.

With that number, you can condition water properly using a dedicated product like X‑Change, which sequesters calcium, magnesium and iron ions before they bind with glyphosate.

Download the X-Change Tech Sheet Here

Beware the Shortcuts AMS & Citric Acid

Some growers use straight ammonium sulphate (AMS) or citric acid to “soften” water – but these aren’t true water conditioners.

  • Straight AMS provides ammonium to compete with divalent cations but doesn’t remove them.
  • Straight citric acid can bind cations, but it competes with glyphosate for uptake, making it unreliable.

Bottom Line: these shortcuts offer partial conditioning at best – and may reduce uptake further. If you want reliable performance, choose a conditioner built for glyphosate compatibility – and dose it based on test results.

Example of failed glyphosate control
source ADAS

Formulation & Adjuvants Matter too

Not all glyphosate products are created equal. The active ingredient may be the same, but surfactant systems vary widely.

Cheaper products often use basic surfactants that struggle to penetrate waxy leaves or cope with dry, dusty conditions.

This is where adjuvants like Validate make a difference: Improve coverage, reduce evaporation, aid penetration. Counteract the impact of hard water cations.

Download the Validate Tech Sheet Here

BEWARE

“Glyphosate resistance concerns every farmer”

John Cussans
Principal Weed Scientist, ADAS

Protecting Glyphosate for the Long Term

Glyphosate is a cornerstone of modern UK farming — valued for its broad-spectrum weed control, reliability, and role in supporting sustainable practices like reduced tillage and cover cropping. But its future depends on how we use it today.

Glyphosate resistance is no longer a global issue – it’s happening here in the UK – confirmed in Italian ryegrass – other species could follow.

Weakened performance from water quality, poor conditioning, or ineffective formulation can accelerate resistance.

Good stewardship protects glyohosate’s effectiveness, now and into the future.

The Solution?

You Control the Risk

Glyphosate resistance isn’t inevitable – stewardship prevents it.

Resistance is not just about overuse, its about underperformance. That starts with your water, product choice and timing.

The De Sangosse Glyphosate Stewardship Guide, created with John Cussans, is your practical manual for smarter glyphosate use.

It explains:

  • How water hardness effects glyphosate
  • Why testing matters, and how to do it
  • What makes a good conditioner
  • When and why to use adjuvants
  • Mixing order and water source considerations
  • Resistance management aligned with WRAG best practice
Download Stewardship Guide

Watch and Learn

Short videos to boost your glyphosate strategy

Hard water can cause something we refer to as 'cation lock-up' and compromise pesticide performance. In this graphical video demonstration we show how the herbicide can benefit by the addition of a water conditioner, which sacrificially binds to the cations in the water rendering them inert. This frees up more of the active ingredient dramatically increasing the herbicide's efficacy.
Hard water can compromise pesticide performance. In this video Rob Suckling at De Sangosse demonstrates how to use a TDS meter in order to identify water that may suffer from the issue of 'cation lock-up'. Such water would benefit from being treated by water conditioners.
In this video Rob Suckling at De Sangosse demonstrates the efficacy of using water conditioners in order to treat hard water and prevent the problem of 'cation lock-up'.
There is an inherent problem with citric acid and fulvic humic acids. In this video Rob Suckling at De Sangosse dives into the issue, sorting out the facts from the fiction and goes into the chemical details.

Get Your Questions Answered

The Facts on Water and Glyphosate

Hard water contains high levels of calcium and magnesium ions. These positively charged ions (cations) react with the negatively charged glyphosate molecule, reducing its availability. The harder your water, the more glyphosate will get locked up before it ever reaches the weed.
Yes. Clear water can still contain high levels of dissolved minerals like calcium, iron and magnesium, which you can’t see. Even moderate hardness can affect glyphosate uptake. A simple hardness test can reveal hidden problems – and water treatment is a low-cost insurance against lost performance.
A simple hardness test with a digital meter, which measures total dissolved solids in the water, will give you a good indication of water hardness. With that, you can apply the right amount of water conditioner. It’s important to know the degree of water hardness so that you add the right dose of water conditioner to your spray water. Water conditioner rates of use are recommended based on water hardness. Under-dosing may result in glyphosate lock-up, while over-dosing means you spend out unnecessarily. Test don’t guess.
Rainwater is usually soft, but it’s not risk-free. If collected from metal roofs, tanks or gutters, it can contain metal residues that interfere with glyphosate. And storing rainwater consider the storage material. Testing your water every now and then is still advised. It’s a simple step with a digital test meter – best to be sure!
Reduced performance from water quality issues can be gradual and easily mistaken for resistance, poor timing, or nozzle choice. As environmental conditions become more variable and weed resistance pressures increase, it’s essential to eliminate every avoidable risk. Treating water is one of the easiest and most effective steps you can take.
Yes – where water hardness is over 150ppm calcium carbonate to avoid significant lock-up. It’s the most reliable way to ensure your glyphosate is working to its full potential.
Always add the water conditioner first, before glyphosate or other products. This ensures the conditioner reacts with water hardness and contaminants, not with glyphosate. Mixing sequence matters – incorrect order will negate the benefit of using a conditioner.

AMS doesn’t actually remove hardness ions – it simply provides ammonium, which serves as a competition agent for divalent cations to form glyphosate salts. Because of its competitive action, these products are said to provide partial water conditioning.

Citric acid can bind with cations effectively, but its ability to complex is pH dependent. Glyphosate’s acidity makes citric acid a poor choice of water conditioner. Citric acid is often used to enhance uptake of foliar applied trace elements and is effective in doing so. However, this means citric acid-metal complexes compete with glyphosate for uptake through the plant cuticle, leading to slower uptake. It’s a shortcut that often causes more issues than it solves.

If you want reliable glyphosate performance, it’s better to use a true water conditioner that’s specifically formulated to tackle hard water ions – and dose it based on testing, not habit.

Yes - even premium brands can lose efficacy in hard water. Some cheaper glyphosates may also contain less effective surfactants, which makes using both a water conditioner and adjuvant even more critical.

Yes. Glyphosate-resistant Italian ryegrass has already been confirmed in the UK, with further suspected cases being investigated. Survivors increase resistance risk.

Glyphosate Stewardship

Follow WRAG Guidelines

Protect your farm’s future by following WRAG’s six golden rules:

  • Always use the right dose
  • Treat weeds at the right time
  • Use the right water quality
  • Minimise the number of applications
  • Use alternatives where possible
  • Monitor, record, and respond

If you suspect resistance, send samples to ADAS to confirm the cause

Click here to visit ADAS's website
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